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Technology of Tissue Engineering (TTE)5 ECTS (englische Bezeichnung: Technology of Tissue Engineering)
(Prüfungsordnungsmodul: Technology of Tissue Engineering (TechTE))
Modulverantwortliche/r: Martin Christian Vielreicher, Liliana Liverani Lehrende:
Martin Christian Vielreicher, Aldo R. Boccaccini, Liliana Liverani, Oliver Friedrich, Michael Haug
Startsemester: |
SS 2022 | Dauer: |
1 Semester | Turnus: |
jährlich (SS) |
Präsenzzeit: |
45 Std. | Eigenstudium: |
105 Std. | Sprache: |
Englisch |
Lehrveranstaltungen:
Details zu den einzelnen Terminen der Vorlesung sind im StudOn Kurs "Schedule & TOC TTE WPF MA" als Datei abgelegt
Inhalt:
- Biomaterials for scaffolds
Biodegradable polymers, composites and bioactive ceramics/glasses
Technologies for the processing of tissue scaffolds
3D Bioprinting and electrospinning methods
High-resolution deep scaffold imaging: 2-photon imaging, Second Harmonic Generation imaging, light sheet imaging, examples from TE using biomaterials
Top-down TE, decellularization/recellularizartion – common con-cepts, challenges, different protocols and chemical processing, opti-cal clearing of bio-scaffolds for 2-photon imaging
Selected decell-/recell systems: lung, heart, kidney and required bio-reactor technologies
Challenges in skeletal muscle TE and MyoBio bioreactor technology (related to prac class)
Lernziele und Kompetenzen:
Students
understand the importance of different concepts in tissue engineering (TE)
know the materials most commonly used in biomaterials, as well as their production and characterization
are familiar with the processing and use of different types of materials such as metals, ceramics and polymers as scaffold structures in TE
conceive the relevance of biomaterials in Tissue Engineering and Regenerative Medicine
are competent to distinguish between the advantages of named biomaterials over others in tissue reconstruction according to the physico-chemical requirements and the cellular seeding prerequisites
apply the different approaches of bottom-up and top-down TE according to respective research questions and applications in Medicine and Industry
are able to choose appropriate optical readout and sensor technologies to monitor the maturation and remodelling of scaffolds by seeded/printed cells
are able to conceptualise bioreactors for tissue maturation according to the target tissue biophysical, physico-chemical and physiological needs
are able to critically evaluate scientific publications on the lecture topics in the accompanying exercise classes (“Übung”) and present study contents and analyses in an oral presentation to the class
Literatur:
- Boccaccini, et al. (eds.): Tissue engineering using ceramics and polymers; Elsevier Woodhead, Cambridge, 2014
Polak, Mantalaris, Harding (eds.): Advances in Tissue Engineering; Oxford u.a., 2010
Hench, Jones (eds.): Biomaterials, artificial organs and tissue engineering; Oxford, 2005
Reviews on organ decell-/recell, e.g. Scarritt et al. (2015) A review of cellulariza-tion strategies for tissue engineering of whole organs. Front Bioeng Biotechnol 3:43
Weitere Informationen:
Schlüsselwörter: Tissue Engineering
www: https://www.mbt.tf.fau.de/
Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan:
- Life Science Engineering (Master of Science)
(Po-Vers. 2019w | TechFak | Life Science Engineering (Master of Science) | Gesamtkonto | Wahlpflichtmodule | Technology of Tissue Engineering (TechTE))
Studien-/Prüfungsleistungen:
Technology of Tissue Engineering (TechTE) (Prüfungsnummer: 44761)
(englischer Titel: Technology of Tissue Engineering)
zugeh. "mein campus"-Prüfung: | - 44761 Technology of Tissue Engineering (TechTE) (Gewichtung: 100.0 %, Prüfung, Form: variabel, Drittelnoten (mit 4,3), Dauer: -, 5 ECTS, Prüfung).
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- Prüfungsleistung, Klausur, Dauer (in Minuten): 120, benotet, 5 ECTS
- Anteil an der Berechnung der Modulnote: 100.0 %
- Prüfungssprache: Deutsch
- Erstablegung: SS 2022, 1. Wdh.: WS 2022/2023
1. Prüfer: | Boccaccini/Friedrich (T10052) |
- Termin: 13.10.2022
Termin: 13.10.2022
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