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Sequence Analysis and Statistical Genomics (ILS-MA-B14)5 ECTS (englische Bezeichnung: Sequenzanalyse und statistische Genomik)
Modulverantwortliche/r: Leila Taher Lehrende:
Leila Taher
Startsemester: |
SS 2018 | Dauer: |
1 Semester | Turnus: |
jährlich (SS) |
Präsenzzeit: |
60 Std. | Eigenstudium: |
90 Std. | Sprache: |
Englisch |
Lehrveranstaltungen:
Empfohlene Voraussetzungen:
none
Inhalt:
The course aims to present some of the most basic algorithms and statistical models for DNA sequence analysis. It focuses on teaching students how to formulate a problem as a mathematical and computational problem, and then solve it using efficient algorithms and appropriate statistical methods. Lecture:
The lectures will cover basic data visualization and summarization, statistical methods, parameter estimation, hypothesis testing, sequence alignment and genome assembly algorithms, population variation, and genome association studies. Computer Lab:
Students will work on problems and through statistical analyses using the freely available software R.
Lernziele und Kompetenzen:
The students
appreciate the stochastic nature of biological phenomena
summarize and visualize data
understand some commonly used algorithms in genomics
understand the mathematical models behind population association studies
choose appropriate statistical methods to assess statistical significance
critically evaluate and interpret statistical methods used in primary research articles
implement a variety of analytical tasks on real datasets
Literatur:
Bioinformatics for Biologists (Cambridge University Press)
Biological Sequence Analysis (Cambridge University Press)
Algorithms on Strings, Trees, and Sequences (Cambridge University Press)
Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan: Das Modul ist im Kontext der folgenden Studienfächer/Vertiefungsrichtungen verwendbar:
- Zell- und Molekularbiologie (Master of Science)
(Po-Vers. 2015w | NatFak | Zell- und Molekularbiologie (Master of Science) | Nichtbiologisches Wahlmodul | Sequence Analysis and Statistical Genomics)
Studien-/Prüfungsleistungen:
Graded homework: Sequence Analysis and Statistical Genomics (Prüfungsnummer: 83801)
- Prüfungsleistung, Hausarbeit, benotet, 5 ECTS
- Anteil an der Berechnung der Modulnote: 100.0 %
- weitere Erläuterungen:
homework assignments approx. 10 pages
- Erstablegung: SS 2018
- Termin: 24.07.2018, 15:30 Uhr
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