Research project

Quantitative DECT with prior atlas knowledge

Dual-Energy CT (DECT) uses two different x-ray spectra simultaneously. This technique enables decomposition of images into the underlying materials by detecting the different attenuation of materials at different x-ray spectra. Thus, the diagnostic significance of DECT is improved compared to single-energy CT. So far, the method of material decomposition is only efficient for certain organs and works only with organ-specific parameters. The organ-specific parameters have to be given by the user manually, and the parameters should be chosen patient- specifically. This project aims at decomposing the materials with anatomy knowledge automatically. An atlas provides the prior knowledge - the anatomic structures. The anatomy knowledge allows then automatic decomposition and classification of the different materials. This project is in cooperation with the German Cancer Research Center (DKFZ) Heidelberg and the University Hospital Erlangen.

Project manager:
Prof. Dr.-Ing. habil. Andreas Maier

Project participants:
Shuqing Chen, M. Sc.

Keywords:
DECT; atlas registration; materials decomposition

Duration: 1.6.2016 - 31.5.2019

Contact:
Maier, Andreas
Phone +49 9131 85 27883, Fax +49 9131 85 27270, E-Mail: andreas.maier@fau.de

Publications

Chen, Shuqing ; Zhong, Xia ; Hu, Shiyang ; Dorn, Sabrina ; Kachelriess, Marc ; Lell, Michael ; Maier, Andreas: Automatic Multi-Organ Segmentation in Dual Energy CT using 3D Fully Convolutional Network. In: van Ginneken, Bram ; Welling, Max (Ed.) : MIDL (International Conference on Medical Imaging with Deep Learning Amsterdam 4-6th, July 2018). 2018, pp n.a..

Dorn, Sabrina ; Chen, Shuqing ; Pisana, Francesco ; Özdemir, Mahmut ; Maier, Joscha ; Sawall, Stefan ; Knaup, Michael ; Maier, Andreas ; Lell, Michael ; Kachelrieß, Marc: Context-sensitive organspecific evaluation and analysis of dual energy computed tomography (DECT). In: European Society of Radiology (Ed.) : European Congress of Radiology (ECR) (European Congress of Radiology (ECR) Vienna, Austria February 28 – March 4, 2018). 2018, pp 2018.

Chen, Shuqing ; Dorn, Sabrina ; Lell, Michael ; Kachelriess, Marc ; Maier, Andreas: Manifold Learning-based Data Sampling for Model Training. In: Bildverarbeitung für die Medizin: Algorithmen-Systeme-Anwendungen (Ed.) : Informatik-Aktuell (Bildverarbeitung für die Medizin 2018 Erlangen 11.-13.03.2018). Germany : Springer, 2018, pp 269-274. - ISBN 978-3-662-56537-7

Dorn, Sabrina ; Chen, Shuqing ; Sawall, Stefan ; Simons, David ; May, Matthias ; Maier, Joscha ; Knaup, Michael ; Schlemmer, Heinz-Peter ; Maier, Andreas ; Lell, Micheal M. ; Kachelriess, Marc: Organ-specific context-sensitive CT image reconstruction and display. In: Joseph Y. Lo ; Taly Gilat Schmidt ; Guang-Hong Chen (Ed.) : Proc.SPIE (Medical Imaging 2018: Physics of Medical Imaging Houston, US 10-15 FEBRUARY 2018). 2018, pp 10573-10573-7.

Dorn, Sabrina ; Chen, Shuqing ; Sawall, Stefan ; Maier, Joscha ; Knaup, Michael ; Maier, Andreas ; Lell, Michael ; Kachelrieß, Marc: Prior-based multi material decomposition (PBMMD) for dual energy CT. In: Frederic Noo (Ed.) : the fifth edition of The International Conference on Image Formation in X-ray Computed Tomography (the fifth edition of The International Conference on Image Formation in X-ray Computed Tomography Salt Lake City, US 21-23.05). 2018, pp 106-109.

Chen, Shuqing ; Roth, Holger ; Dorn, Sabrina ; May, Matthias ; Cavallaro, Alexander ; Lell, Michael ; Kachelrieß, Marc ; Oda, Hirohisa ; Mori, Kensaku ; Maier, Andreas: Towards Automatic Abdominal Multi-Organ Segmentation in Dual Energy CT using Cascaded 3D Fully Convolutional Network. In: Noo, Frederic (Ed.) : the fifth edition of The International Conference on Image Formation in X-ray Computed Tomography (the fifth edition of The International Conference on Image Formation in X-ray Computed Tomography Salt lake city, US 21-23.05.2018). 2018, pp 395-398.

Sabrina Dorn ; Chen, Shuqing ; Stefan Sawall ; Joscha Maier ; Michael Knaup ; Monika Uhrig ; Heinz-Peter Schlemmer ; Maier, Andreas ; Michael Lell ; Marc Kachelrieß: Towards context-sensitive CT imaging — organ-specific image formation for single (SECT) and dual energy computed tomography (DECT). In: Medical Physics (2018), No. 45(10), pp 4541-4557
[doi>10.1002/mp.13127]

Chen, Shuqing ; Endres, Jürgen ; Dorn, Sabrina ; Maier, Joscha ; Lell, Michael ; Kachelrieß, Marc ; Maier, Andreas: A Feasibility Study of Automatic Multi-Organ Segmentation Using Probabilistic Atlas. In: Maier-Hein, Klaus Hermann ; Deserno, Thomas Martin ; Handels, Heinz ; Tolxdorff, Thomas (Ed.) : Bildverarbeitung für die Medizin: Algorithmen-Systeme-Anwendungen. (Bildverarbeitung für die Medizin 2017 Heidelberg 12.-14.03.2017). 2017, pp 218-223. - ISBN 978-3-662-54345-0
[doi>10.1007/978-3-662-54345-0_50]

Dorn, Sabrina ; Chen, Shuqing ; Pisana, Francesco ; Maier, Joscha ; Knaup, Michael ; Sawall, Stefan ; Maier, Andreas ; Lell, Michael ; Kachelriess, Marc: Organ-specific context-sensitive single and dual energy CT (DECT) image reconstruction, display and analysis. In: RSNA (Ed.) : n 103rd Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA) (RSNA 2017 Chicago , USA 26 Nov. - 1 Dec., 2017). 2017, pp 2017.