Research project

In industrialized countries, neurovascular diseases like intracranial aneurysms are a major cause of stroke and death, often combined with permanent disabilities. Interventional methods and new developments in imaging technology significantly extended therapeutic possibilities and are capable of enhancing the treatment outcome. However, the opportunity for increasing the treatment efficiency of cerebral vascular diseases, particularly in terms of a personalized therapy, and hence an increased treatment quality in combination with the reduction of treatment costs is not exhausted by far. Hemodynamic stress plays a major role for the development of cerebral aneurysms and stenoses as well as for the long-term success of their treatment.

Primary goal of this interdisciplinary project is the development of new dimensions of hemodynamic simulations within the interventional environment and hence the development towards a personalized therapy for neurovascular diseases.

The overall aim of this interdisciplinary research project is the development and implementation of a multimodal platform for an automized temporal and spatial simulation of cerebral hemodynamics directly within the neurointerventional environment. A special focus is put on the optimization of segmentation algorithms as significant precondition for a reliable simulation, as well as on virtual angiography and device- based virtual therapy planning, respectively.

In the second part of the project these algorithms will be implemented in the interventional environment, embedded into the workflow. A multitude of hemodynamic features will then be evaluated using clinical reference values.