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Advanced fundus imaging for early detection of eye diseases

New optical scanning techniques like optical coherent tomography (OCT) allow high resolution imaging of the depth structure of the retina. The goal of the project is to improve the ability for early detection of eye diseases and to diagnose their progress based on this new imaging techniques. The focus lies on glaucoma diseases. Methods that provide ophthalmologists new possibilities to judge image data should be developed. An example for such a method is an automated segmentation and thickness measurement of the nerve fiber layer. Furthermore, the outcomings of the image processing must be visualised in an appropriate manner. Within the collaboration of the ophthalmologic department of the university clinic Erlangen and the institute for pattern recognition we design new methods for image enhancement. The war OCT data is denoised an motion artifacts are corrected. The ophthalmologic department brings in its experience in the development and application of new methods in ophthalmology, particularly from the SFB 539. Together with the competence of the institute for pattern recognition in medical image processing this is an excellent base for the project.
Project manager:
Prof. Dr.-Ing. Joachim Hornegger, Dr.-Ing. Ralf-Peter Tornow

Project participants:
Dipl.-Inf. Markus Mayer, Dr.-Ing. Ralf-Peter Tornow, Lenke Laurik

Keywords:
Optical Coherence Tomography; OCT; retina; segmentation; glaucoma; visualisation

Duration: 1.9.2007 - 1.12.2012

Sponsored by:
School of Advanced Optical Technologies (SAOT)

Contact:
Mayer, Markus
E-Mail: markus.mayer@cs.fau.de
Publications
Mayer, Markus: Automatic Nerve Fiber Layer Segmentation and Geometry Correction.Talk: Annual Meeting, The Association for Research in Vision and Ophthalmology, Inc. (ARVO), Fort Lauderdale, Florida, USA, 28.04..2008
Mayer, Markus ; Tornow, Ralf P. ; Hornegger, Joachim ; Kruse, Friedrich E.: Fuzzy C-means Clustering For Retinal Layer Segmentation On High Resolution OCT Images. In: Jan, Jiri ; Kozumplik, Jiri ; Provanznik, Ivo (Ed.) : Analysis of Biomedical Signals and Images, Proceedings of the Biosignal 2008 International Eurasip Conference (Biosignal Brno, Czech Republic 29.6.2008-01.07.2008). Vol. 19, 1. Edition Brno, Czech Republic : v, 2008, pp no pagination. - ISBN 978-80-214-3613-8
Wagner, Martin ; Borsdorf, Anja ; Mayer, Markus ; Tornow Ralf: Wavelet Based Approach to Multiple-Frame Denoising of OCT-Images. In: Hubertus, Feußner (Ed.) : Proceedings of the 5th Russian Bavarian Conference on Bio-Medical Engineering (RBC) (5th Russian Bavarian Conference on Bio-Medical Engineering (RBC) München). 2009, pp 67-69. - ISBN 978-3-00-029049-7
Mayer, Markus ; Hornegger, Joachim ; Mardin, Christian Y. ; Tornow, Ralf-Peter: Retinal Nerve Fiber Layer Segmentation on FD-OCT Scans of Normal Subjects and Glaucoma Patients. In: Biomedical Optics Express 1 (2010), No. 5, pp 1358-1383

Institution: Chair of Computer Science 5 (Pattern Recognition)
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