| Assessment of cardiac rotation and twist from bi-plane angiograms Various types of heart disease change left ventricular
(LV) rotation. Measures of LV rotation are correlated
with early onset symptoms of heart
disease, such as subclinical aortic stenosis and
diastolic dysfunction. Noninvasive assessment of LV
torsion, however, is challenging with modalities
other than tagged MRI, which oftentimes is
contraindicated due to metal implants.
Coronary angiography is the imaging modality of choice
for heart diseases. Virtually all clinical cases undergo
this procedure at least once. In coronary
angiography the heart arteries are selectively contrasted
using a catheter that is inserted into the cardiac vessel
system, making them clearly visible
in projection X-ray imaging. As the coronary arteries are
attached to the heart’s surface, they follow LV torsion.
The proposed research project aims at the development of
a segmentation and reconstruction algorithm for 3D + t
coronary angiograms in order to
fully describe myocardial surface motion including
torsion that is invisible in Computed Tomography and
Magnetic Resonance Imaging. As the
proposed project re-uses image data from standard imaging
protocols, no additional radiation dose and discomfort is
caused to the patient.
| Project manager:
Prof. Dr.-Ing. Joachim Hornegger
Project participants:
Prof. Dr.-Ing. habil. Andreas Maier, Prof. Dr.-Ing. Joachim Hornegger, Dr.-Ing. Mathias Unberath
Keywords:
cardiac rotation; torsion; twist; angiography; vessel segmentation; CT
Start: 15.11.2014
Sponsored by:
Graduate School of Advanced Optical Technologies
Contact:
Unberath, Mathias
Phone +49 9131 85 28982, Fax +49 9131 85 27270, E-Mail: mathias.unberath@fau.de
|