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Image Processing for Talbot-Lau X-ray Phase Contrast

Grating-based Talbot-Lau X-ray Interferometry is a novel imaging modality. Compared to standard absorption X-ray imaging, it enables the acquisition of differential phase contrast images. These images correspond to the electron density of the scanned specimen. Furthermore, so-called dark-field images are obtained. These images can visualize density inhomogeneities at micrometer scale.
The goal of the project is to improve the image quality in Talbot-Lau X-ray Imaging. Typically, Talbot-Lau setups are sensitive to vibrations and thermal effects, as the structure size of the employed gratings lies in the micrometer range. Thus, the generated images may be affected by image artifacts. These artifacts should be removed using image processing. The final goal is to achieve a consistent image quality outside of laboratory conditions.
Project manager:
PD Dr.-Ing. Christian Riess

Project participants:
Sebastian Käppler, M. Sc.

Keywords:
Phase Contrast, Talbot-Lau, X-ray, Image Processing

Duration: 1.11.2014 - 31.12.2017

Sponsored by:
International Max Planck Research School Physics of Light (IMPRS-PL)

Contact:
Käppler, Sebastian
Phone +49 9131 85 27894, Fax +49 9131 85 27270, E-Mail: sebastian.kaeppler@fau.de
Publications
Käppler, Sebastian ; Wandner, Johannes ; Weber, Thomas ; Maier, Andreas ; Anton, Gisela ; Hornegger, Joachim ; Riess, Christian: Shading Correction for Grating-based Differential Phase Contrast X-ray Imaging. In: IEEE (Ed.) : 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC) ((IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) 2014) Seattle, WA, USA 08.11.2014). 2014, pp 00-00.
Käppler, Sebastian ; Bayer, Florian ; Weber, Thomas ; Maier, Andreas ; Anton, Gisela ; Hornegger, Joachim ; Beckmann, Matthias W. ; Fasching, Peter Andreas ; Hartmann, Arndt ; Heindl, Felix ; Michel, Thilo ; Özgül, Gülümser ; Pelzer, Georg ; Rauh, Claudia ; Rieger, Jens ; Schulz-Wendtland, Rüdiger ; Uder, Michael ; Wachter, David Lukas ; Wenkel, Evelyn ; Riess, Christian: Signal Decomposition for X-ray Dark-field Imaging. In: MICCAI Society (Ed.) : Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2014 (International Conference on Medical Image Computing and Computer-Assisted Intervention Boston, MA, USA 15.09.2014). Heidelberg : Springer International Publishing, 2014, pp 170-177. (Lecture Notes in Computer Science Vol. 8673) - ISBN 978-3-319-10404-1
[doi>10.1007/978-3-319-10404-1_22]
Käppler, Sebastian ; Maier, Andreas ; Riess, Christian: Differential Tomography: Influence of Sensitivity Direction and Noise-suppressing Windows. In: Noo, Frederic (Ed.) : Proceedings of the 5th International Conference on Image Formation in X-ray Computed Tomography (CT-Meeting Salt Lake City, UT, USA 20.-23.05.2018). 2018, pp 119-122.
Horn, Florian ; Leghissa, Martino ; Käppler, Sebastian ; Pelzer, Georg ; Rieger, Jens ; Seifert, Maria ; Wandner, Johannes ; Weber, Thomas ; Michel, Thilo ; Riess, Christian ; Anton, Gisela: Implementation of a Talbot-Lau interferometer in a clinical-like c-arm setup: A feasibility study. In: Scientific Reports 8 (2018), pp 2325
[doi>10.1038/s41598-018-19482-z]
Horn, Florian ; Gelse, Kolja ; Jabari, Samir ; Hauke, Christian ; Käppler, Sebastian ; Ludwig, Veronika ; Meyer, Pascal ; Michel, Thilo ; Mohr, Jürgen ; Pelzer, Georg ; Rieger, Jens ; Riess, Christian ; Seifert, Maria ; Anton, Gisela: High-energy x-ray Talbot–Lau radiography of a human knee. In: Physics in Medicine and Biology 62 (2017), No. 16, pp 6729-6745
[doi>10.1088/1361-6560/aa7721]
Käppler, Sebastian ; Rieger, Jens ; Pelzer, Georg ; Horn, Florian ; Michel, Thilo ; Maier, Andreas ; Anton, Gisela ; Riess, Christian: Improved reconstruction of phase-stepping data for Talbot–Lau x-ray imaging. In: Journal of Medical Imaging 4 (2017), No. 3, pp 034005
[doi>10.1117/1.JMI.4.3.034005]
Schiffers, Florian ; Käppler, Sebastian ; Pelzer, Georg ; Wolf, Andreas ; Maier, Andreas ; Anton, Gisela ; Riess, Christian: Polychromatic Maximum Likelihood Reconstruction for Talbot-Lau X-ray Tomography. In: Wang, Ge ; Mou, Xuanqin (Ed.) : Proceedings of Fully3D'17 (14th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine Xi'an, China 18-23.06.2017). 2017, pp 249-255.
Käppler, Sebastian ; Seifert, Maria ; Horn, Florian ; Pelzer, Georg ; Rieger, Jens ; Michel, Thilo ; Maier, Andreas ; Anton, Gisela ; Riess, Christian: Talbot-Lau X-ray phase contrast for tiling-based acquisitions without reference scanning. In: Medical Physics 44 (2017), No. 5, pp 1886-1898
[doi>10.1002/mp.12200]

Institution: Chair of Computer Science 5 (Pattern Recognition)
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