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Phonation, articulation, and prosody analysis of speech of people with Parkinson’s disease in pre-clinics and advanced stagesGeneral Aim
To analyze, characterize, and quantify the affection on
phonation, articulation, and prosody due to the presence of
the disease, in order to develop computational-aided tools
to help in the diagnosis and assessment of people with PD.Specific Aims To analyze and implement measurements for the assessment of
the phonation, articulation, and prosodic capability of
people with PD.
To develop methods able to classify between patients with PD
and age-matched healthy controls.
To develop methods able to predict the neurological state of
PD patients according to the motor section of the Unified
Parkinson’s Disease Rating Scale (UPDRS-III).
To develop a computer-aided tool for the assessment of the
speech of people with PD.
To study and determine possible patterns in speech to
predict the risk of people to develop PD due to specific
genetics condition. Population to be Studied
Inherited Parkinson: people carrying a mutation on the
PARKIN gen, and exhibiting symptoms of the PD.
Relatives of Inherited Parkinson: relatives of people
carrying a mutation of PARKIN, but without any symptom of
PD.
Idiopathic Parkinson: people already diagnosed with PD but
not carrying any mutation.
Control: people without any sign of PD or any other
neurological disorder and dementia. Expected Results
To identify speech patterns as possible bio-markers of PD in
a pre-clinics stage.
A computer-aided tool for the automatic assessment of speech
of people with PD. | Project manager:
Dr.-Ing. Jesús Francisco Vargas-Bonilla, Assistant Professor, Universidad de Antioquia (UdeA), Colombia
Project participants:
Dr.-Ing. Julián David Arias-Londońo, UdeA, Prof. Dr.-Ing. Elmar Nöth, Prof. Dr.-Ing. Germán Castellanos-Dominguez, Universidad Nacional de Colombia, branch Manizales, Prof. Dr.-Ing. Miguel Ángel Ferrer-Ballester, Universidad de Las Palmas de Gran Canaria (ULPGC), Espańa, Prof. Dr.-Ing. Pedro Gómez-Vilda, Universidad Politécnica de Madrid, Espańa , Dr.-Ing. Carlos Manuel Travieso-González, ULPGC, Dr.-Ing. Jesús Bernardino Alonso, ULPGC, Dr.-Ing. Juan Rafael Orozco-Arroyave, Juan Camilo Vásquez, Elkyn Belalcázar Bolańos, Tatiana Villa, Nicanor García, Gabriel Zapata, Tomás Arias-Vergara
Keywords:
Parkinson's disease; speech analysis; neurlogical state; genetics
Duration: 1.7.2013 - 31.7.2016
Sponsored by:
COLCIENCIAS, Colombia
Universidad de Antioquia
Contact:
Orozco-Arroyave, Juan Rafael
E-Mail: juan.rafael.orozco@fau.de
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Orozco-Arroyave, Juan Rafael ; Vargas-Bonila, Jesús Francisco ; Arias-Londońo, Julián ; Skodda, Sabine ; Rusz, Jan ; Daqrouq, Kaled ; Hönig, Florian ; Nöth, Elmar: Automatic detection of Parkinson's disease in continuous speech spoken in three different languages. In: Journal of the Acoustical Society of America - JASA 139 (2016), No. 1, pp 20
[doi>10.1121/1.4939739] | | Hemmerling, Daria ; Orozco-Arroyave, Juan Rafael ; Skalski, A. ; Gajda, J. ; Nöth, Elmar: Automatic detection of Parkinson’s disease based on modulated vowels. In: International Speech Communication Association (Ed.) : Proceedings of the 17th INTERSPEECH (Pathological Speech Analysis San Francisco, CA, USA 09.2016). 2016, pp 1190-1194. | | Galaz, Z. ; Mzourek, Z. ; Mekyska, J. ; Smekal, Z. ; Kiska, T. ; Roktorova, I. ; Orozco-Arroyave, Juan Rafael ; Daoudi, K.: Degree of Parkinson’s Disease Severity Estimation Based on Speech Signal Processing. In: IEEE (Ed.) : IEEE 39th International Conference on Telecommunications and Signal Processing (Pathological Speech Analysis Vienna, Austria 06.2016). 2016, pp 1-4. | | Arias-Vergara, Tomás ; Vásquez-Correa, Juan Camilo ; Orozco-Arroyave, Juan Rafael ; Vargas-Bonilla, Jesús Francisco ; Haderlein, Tino ; Nöth, Elmar: Gender-dependent GMM-UBM for Tracking Parkinson's Disease Progression from Speech. In: Informationstechnische Gesellschaft im VDE (Ed.) : Speech Communication - 12. ITG Fachtagung Sprachkommunikation (12. ITG Fachtagung Sprachkommunikation Paderborn 05.-07.10.2016). Berlin : VDE Verlag, 2016, pp 259-263. (ITG-Fachberichte Vol. 267) - ISBN 978-3-8007-4275-2 | | Belalcazar-Bolanos, Elkyn ; Orozco-Arroyave, Juan Rafael ; Vargas-Bonila, Jesus Francisco ; Haderlein, Tino ; Nöth, Elmar: Glottal Flow Patterns Analyses for Parkinson’s Disease Detection: Acoustic and Nonlinear Approaches. In: Sojka, Petr ; Horak, Ales ; Kopecek, Ivan ; Pala, Karel (Ed.) : Proc. Text, Speech and Dialogue; 19th International Conference, TSD 2016 (Pathological Speech Analysis Brno 09.2016). 2016, pp 1-8. | | Arias-Vergara, Tomás ; Vásquez-Correa, Juan Camilo ; Orozco-Arroyave, Juan Rafael ; Vargas-Bonilla, Jesús Francisco ; Nöth, Elmar: Parkinson's disease progression assessment from speech using GMM-UBM. In: International Speech Communication Association (Ed.) : Proceedings of the 17th INTERSPEECH (Pathological Speech Analysis San Francisco, CA, USA 09.2016). San Francisco : ISCA, 2016, pp 1933-1937. | | Orozco-Arroyave, Juan Rafael ; Vásquez-Correa, Juan Camilo ; Hönig, Florian ; Arias-Londońo, Julián ; Vargas-Bonilla, Jesús Francisco ; Skodda, Sabine ; Rusz, Jan ; Nöth, Elmar: Towards an automatic monitoring of the neurological state of Parkinson's patients from speech. In: IEEE (Ed.) : Proceedings of the 41st IEEE ICASSP (PATHOLOGICAL SPEECH ANALYSIS Shanghai, China 05.2016). 2016, pp 6490-6494. | | Vásquez-Correa, Juan Camilo ; Arias-Vergara, Tomás ; Orozco-Arroyave, Juan Rafael ; Vargas-Bonilla, Jesús Francisco ; Arias-Londońo, Julián David ; Nöth, Elmar: Automatic detection of Parkinson's disease from continuous speech recorded in non-controlled noise conditions. In: International Speech Communication Association (Ed.) : Proceedings of the 16th INTERSPEECH (16th Annual Conference of the International Speech Communication Association (INTERSPEECH) Dresden, Germany 07.09.2015). 2015, pp 105-109. | | Orozco-Arroyave, Juan Rafael ; Haderlein, Tino ; Nöth, Elmar: Automatic Detection of Parkinson's Disease in Reverberant Environments. In: Kral, Pavel ; Matousek, Vaclav (Ed.) : Proc. Text, Speech and Dialogue; 18th International Conference, TSD 2015 (Text, Speech and Dialogue; 18th International Conference, TSD 2015 Pilsen, Czech Republic 14.-17.09.2015). Berlin : Springer, 2015, pp 80-87. (LNAI Vol. 9302) | Orozco-Arroyave, Juan Rafael ; Belalcázar-Bolańos, Elkyn Alexander ; Arias-Londońo, Julián David ; Vargas-Bonilla, Jesús Francisco ; Skodda, Sabine ; Rusz, Jan ; Daqrouq, Khaled ; Hönig, Florian ; Nöth, Elmar: Chracterization methods for the detection of multiple voice disorders: neurological, functional, and organic diseases. In: IEEE Journal of Biomedical and Health Informatics (2015), No. 1, pp 1-9
[doi>10.1109/JBHI.2015.2467375] | | Villa-Cańas, Tatiana ; Arias-Londońo, Julián David ; Orozco-Arroyave, Juan Rafael ; Vargas-Bonilla, Jesús Francisco ; Nöth, Elmar: Low-frequency components analysis in running speech for the automatic detection of Parkinson's disease. In: International Speech Communication Association (Ed.) : Proceedings of the 16th INTERSPEECH (16th Annual Conference of the International Speech Communication Association (INTERSPEECH) Dresden, Germany 06.09.2015). 2015, pp 100-104. | Orozco-Arroyave, Juan Rafael ; Hönig, Florian ; Arias-Londońo, Julián David ; Vargas-Bonilla, Jesús Francisco ; Nöth, Elmar: Spectral and cepstral analyses for Parkinson's disease detection in Spanish vowels and words. In: Expert Systems 1 (2015), No. 1, pp 1-10
[doi>10.1111/exsy.12106] | | Schuller, Björn ; Steidl, Stefan ; Batliner, Anton ; Hantke, Simone ; Hönig, Florian ; Orozco-Arroyave, Juan Rafael ; Nöth, Elmar ; Zhang, Yue ; Weninger, Felix: The INTERSPEECH 2015 Computational Paralinguistics Challenge: Nativeness, Parkinson's & Eating Condition. In: ISCA (Ed.) : Proceedings of the 16th Annual Conference of the International Speech Communication Association (INTERSPEECH 2015) (INTERSPEECH 2015 - 16th Annual Conference of the International Speech Communication Association (ISCA) Dresden, Germany 06.10.2015). 2015, pp 478-482. | | Wankerl, Sebastian ; Hönig, Florian ; Batliner, Anton ; Orozco-Arroyave, Juan Rafael ; Nöth, Elmar: Visual Comparison of Speaker Groups. In: ISCA (Ed.) : INTERSPEECH 2015, Proceedings of (INTERSPEECH 2015 Dresden, Germany 06.09.2015-10.09.2015). 2015, pp 2613-2614. | | Orozco-Arroyave, Juan Rafael ; Hönig, Florian ; Arias-Londońo, Julián David ; Vargas-Bonilla, Jesús Francisco ; Skodda, Sabine ; Rusz, Jan ; Nöth, Elmar: Voiced/unvoiced transitions in speech as a potential bio-marker to detect Parkinson's disease. In: International Speech Communication Association (Ed.) : Proceedings of the 16th INTERSPEECH (16th Annual Conference of the International Speech Communication Association (INTERSPEECH) Dresden, Germany 07.09.2015). 2015, pp 95-99. |
Institution: Chair of Computer Science 5 (Pattern Recognition)
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