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3-D Imaging of the heart chambers with C-arm CT

The direct 3-D reconstruction of the heart chamber in the catheter lab provides many advantages. The clinical workflow is optimized due to the fact that the clinical information is directly available at the therapy system. In this project, the focus of the 3-D reconstruction is on the left ventricle.

Regarding the long acquisition time of the C-arm system for the acquisition of the projection images (> 5s), the heart motion has to be considered. In the field of 3-D/4-D reconstruction of coronary arteries, an approach was developed estimating the heart motion from the projection images and compensating the motion in the reconstruction of the volumetric data. This technique is working on sparse data and cannot be applied to the heart chamber reconstruction.

In general, the project comprehends the development of new techniques for 3-D/4-D reconstruction of non-sparse objects.

The analysis can be classified into the following working fields:

  • Analysis and development of algorithms for motion estimation and motion compensating reconstruction algorithms.

  • Analysis and development of optimized acquisition and contrast protocols.

  • Analysis and development of a mathematical 4-D heart model for quantitative evaluation.

  • Analysis and development of models to describe the heart wall motion.

  • Analysis and development of surface models.

Project manager:
Prof. Dr.-Ing. Joachim Hornegger

Project participants:
Dr.-Ing. Kerstin Müller, Dr. Günter Lauritsch, Dr.-Ing. Christopher Rohkohl

Keywords:
Motion compensation; dynamic 3-D reconstruction; cardiac imaging; C-arm CT

Duration: 1.10.2010 - 31.3.2014

Sponsored by:
Siemens AG, Healthcare Sector

Contact:
Müller, Kerstin
E-Mail: kerstin.mueller@cs.fau.de
Publications
Chen, Mingqing ; Zheng, Yefeng ; Müller, Kerstin ; Rohkohl, Christopher ; Lauritsch, Günter ; Boese, Jan ; Funka-Lea, Gareth ; Hornegger, Joachim ; Comaniciu, Dorin: Automatic Extraction of 3D Dynamic Left Ventricle Model From 2D Rotational Angiocardiogram. In: Fichtinger, Gabor ; Martel, Anne ; Peters, Terry (Ed.) : Medical Image Computing and Computer-Assisted Intervention - MICCAI 2011 (14th International Conference on Medical Image Computing and Computer-Assisted Intervention - MICCAI 2011 Toronto, Canada 18.-22.09.2011). Heidelberg, Berlin : Springer, 2011, pp 457-464. - ISBN 978-3-642-23625-9
Chen, Mingqing ; Zheng, Yefeng ; Müller, Kerstin ; Rohkohl, Christopher ; Lauritsch, Günter ; Boese, Jan ; Comaniciu, Dorin: Enhancement of Organ of Interest via Background Subtraction in Cone Beam Rotational Angiocardiogram. In: IEEE (Ed.) : 9th IEEE International Symposium on Biomedical Imaging (ISBI), 2012 (9th IEEE International Symposium on Biomedical Imaging (ISBI), 2012 Barcelona, Spain 02.-05.May.2012). 2012, pp 622-625.
Müller, Kerstin ; Zheng, Yefeng ; Lauritsch, Günter ; Rohkohl, Christopher ; Schwemmer, Chris ; Maier, Andreas ; Fahrig, Rebecca ; Hornegger, Joachim: Evaluation of Interpolation Methods for Motion Compensated Tomographic Reconstruction for Cardiac Angiographic C-arm Data. In: Noo, Frederic (Ed.) : Proceedings of the second international conference on image formation in x-ray computed tomography (Second international conference on image formation in x-ray computed tomography Salt Lake City, Utah, USA 24-27.06.2012). 2012, pp 5-8.
Chen, Mingqing ; Zheng, Yefeng ; Lauritsch, Günter ; Boese, Jan ; Müller, Kerstin ; Rohkohl, Christopher ; Funka-Lea, Gareth ; Comaniciu, Dorin: Left Ventricle Epicardium Estimation in Medical Diagnostic Imaging. Schutzrecht US 2013 / 0004040 A1 examined granted patent (03.01.2013)
Chen, Mingqing ; Zheng, Yefeng ; Lauritsch. Günter ; Boese, Jan ; Müller, Kerstin ; Rohkohl, Christopher ; Funka-Lea, Gareth ; Comaniciu, Dorin: Subtraction of Projection Data in Medical Diagnostic Imaging. Schutzrecht US 2013 / 0004052 A1 examined granted patent (03.01.2013)
Chen, Mingqing ; Zheng, Yefeng ; Wang, Yang ; Müller, Kerstin ; Lauritsch, Günter: Automatic 3D Motion Estimation of Left Ventricle from C-arm Rotational Angiocardiography Using a Prior Motion Model and Learning Based Boundary Detector. In: Mori, Kensaku ; Sakuma, Ichiro ; Sato, Yoshinobu ; Barillot, Christian ; Navab, Nassir (Ed.) : Medical Image Computing and Computer-Assisted Intervention (Medical Image Computing and Computer-Assisted Intervention Nagoya, Japan 22.-26.09.2013). 2013, pp 90-97.
[doi>10.1007/978-3-642-40760-4_12]
Müller, Kerstin ; Schwemmer, Chris ; Hornegger, Joachim ; Zheng, Yefeng ; Wang, Yang ; Lauritsch, Günter ; Rohkohl, Christopher ; Maier, Andreas ; Schultz, Carl ; Fahrig, Rebecca: Evaluation of interpolation methods for surface-based motion compensated tomographic reconstruction for cardiac angiographic C-arm data. In: Medical Physics 40 (2013), No. 3
[doi>10.1118/1.4789593]
Müller, Kerstin ; Rohkohl, Christopher ; Lauritsch, Günter ; Schwemmer, Chris ; Heidbüchel, Hein ; De Buck, Stijn ; Nuyens, Dieter ; Kyriakou, Yiannis ; Köhler, Christoph ; Hornegger, Joachim: 4-D Motion Field Estimation by Combined Multiple Heart Phase Registration (CMHPR) for Cardiac C-arm Data. In: IEEE (Ed.) : 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC) (IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) 2012 Anaheim, CA, USA 29.10-03.11.2012). 2012, pp 3707-3712.
Müller, Kerstin ; Schwemmer, Chris ; Lauritsch, Günter ; Rohkohl, Christopher ; Maier, Andreas ; Heidbüchel, Hein ; De Buck, Stijn ; Nuyens, Dieter ; Kyriakou, Yiannis ; Köhler, Christopher ; Fahrig, Rebecca ; Hornegger, Joachim: Image Artifact Influence on Motion Compensated Tomographic Reconstruction in Cardiac C-arm CT. In: Fully3D committee (Ed.) : Proceedings of the 12th Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine (Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine (Fully3D) Lake Tahoe, CA, USA 16.06-21.06.2013). 2013, pp 98-101.

Institution: Chair of Computer Science 5 (Pattern Recognition)
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