Fatty Acid Composition Quantification in the Liver and Optimization of the used Acquisition and Reconstruction TechniquesIn order to discriminate between diseases of the non-
alcoholic fatty liver disease (NAFLD) spectrum,
additionally to the total amount of deposited liver fat,
knowledge about the relative fractions of different fatty
acids might be valuable. The fatty acids determine the
relative areas under peaks of the multi-peak fat
spectrum, which can be used to measure their degree of
saturation using Magnetic Resonance Imaging (MRI).The aim of this project is to develop a method yielding
accurate information about the fatty acid composition in
the liver using MRI. The technique ought to measure the
fraction of unsaturated, mono-unsaturated, poly-
unsaturated as well as saturated fat in percent with high
enough spatial resolution, such that local changes in the
composition can be captured. This not only includes
proper post-processing of reconstructed MR contrast
images, but also the optimization of the selected
acquisition and reconstruction techniques.
| Project manager:
Prof. Dr.-Ing. habil. Andreas Maier, Dr. Marcel Dominik Nickel
Project participants:
Manuel Schneider, M. Sc.
Keywords:
abdominal MRI; fatty acid composition; liver fat; water-fat quantification
Duration: 1.7.2016 - 30.6.2019
Sponsored by:
Siemens Healthcare GmbH
Contact:
Maier, Andreas
Phone +49 9131 85 27883, Fax +49 9131 85 27270, E-Mail: andreas.maier@fau.de
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