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Structural Biology II: Structure and function relationships in biological macromolecules (StrBio2)7.5 ECTS (englische Bezeichnung: Strukturbiologie II: Struktur-Funktionsbeziehungen in Biologischen Makromolekülen)
Modulverantwortliche/r: Yves Muller Lehrende:
Rainer Böckmann, Yves Muller, Benedikt Schmid
Start semester: |
SS 2016 | Duration: |
1 semester | Cycle: |
jährlich (SS) |
Präsenzzeit: |
120 Std. | Eigenstudium: |
105 Std. | Language: |
Englisch |
Lectures:
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Mastermodul Biotechnik II: Structure und function relationships in biotechnologically relevant macromolecules
(Übung, 6 SWS, Yves Muller, single appointment on 4.4.2016, 9:15 - 10:00, Hörsaal ZMPT; single appointment on 5.4.2016, 9:15 - 10:45, Hörsaal ZMPT; single appointment on 6.4.2016, 9:15 - 10:00, Hörsaal ZMPT; single appointment on 7.4.2016, 9:15 - 10:45, Hörsaal ZMPT; single appointment on 8.4.2016, 9:15 - 10:00, Hörsaal ZMPT; single appointment on 13.4.2016, single appointment on 15.4.2016, single appointment on 20.4.2016, 9:15 - 10:45, SR Biologie; single appointment on 21.4.2016, 9:15 - 10:00, Hörsaal ZMPT; single appointment on 26.4.2016, 9:15 - 12:00, SR Biologie; single appointment on 28.4.2016, 13:15 - 14:45, SR Biologie; from 4.4.2016 to 29.4.2016; LS für Biotechnik, MVC, Henkestraße 91, 91052 Erlangen sowie im Biologikum)
Empfohlene Voraussetzungen:
none
Inhalt:
Seminar talks cover theoretical and methodological approaches for the study of structure-function relationships in proteins with a focus on structural determinants in regulation of protein function. Laboratory course are focused on advanced methods in the study of structure-dynamics-function relationships of proteins. Both experimental (heterologous protein production in eucaryotic cells, X-ray analysis, mutation studies) as well as theoretical methods (atomistic and coarse-grained molecular dynamics simulations) will be addressed. The main part of the practical course is devoted to active cooperation in ongoing research projects of the participating labs.
Lernziele und Kompetenzen:
The students are
acquainted with novel insights, concepts, and methods in the study of protein-dynamics-function relationships
understand state-of-the-art methods in the analysis of protein structure, dynamics, function and their limitations
are able to independently develop working hypotheses, to independently design and conduct experiments
able to present and critically discuss current research articles / their results and defend their conclusions in proper context
Literatur:
introductory articles will be provided electronically
Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan: Das Modul ist im Kontext der folgenden Studienfächer/Vertiefungsrichtungen verwendbar:
- Integrated Life Sciences: Biology, Biomathematics, Biophysics (Master of Science)
(Po-Vers. 2015w | NatFak | Integrated Life Sciences: Biology, Biomathematics, Biophysics (Master of Science) | Module Groups | MG3: Biological Structures and Processes | Mandatory Elective Modules Group 3 | Structural Biology II: Structure und Function Relationships in Biotechnologically Relevant Macromolecules)
Studien-/Prüfungsleistungen:
Portfolio exam Structural Biology II: Structure and Function Relationships in Biotechnologically Relevant Macromolecules (Prüfungsnummer: 22111)
- Prüfungsleistung, mehrteilige Prüfung, benotet, 7.5 ECTS
- Anteil an der Berechnung der Modulnote: 100.0 %
- weitere Erläuterungen:
PL: mündliche Prüfung 30 Min.
PL: mündliches Referat
PL: schriftliches Protokoll
- Erstablegung: SS 2016, 1. Wdh.: WS 2016/2017
1. Prüfer: | Böckmann/Muller |
- Termin: 29.07.2016
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