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Advanced Multimodal Cardiac Modeling and OR IntegrationIn current clinical practice, minimally invasive procedures
are starting to
replace open heart surgeries. As there is no direct view or
access to the
affected anatomy, there is a high demand for predictive
models, sophisticated
planning and operating room (OR) integration tools. In the
context of
transcatheter therapies, such as the Transcatheter Aortic
Valve Implantation
(TAVI), biomarkers of the entire aortic-mitral apparatus
must be extracted in
order to perform patient selection and risk assessment as
well as device
selection and operation optimization. Current methods are
able to extract basic
biomarkers such as diameter, area measurements and C-arm
angulations, but they
fail to model the entire left-heart system and are
neglecting the true
volumetric physiology of the aortic root and leaflets. These
features are
mandatory for extracting advanced biomarkers as well as for
computational
modeling of biomechanics and fluid dynamics.The main research focus lies on the development of novel
segmentation algorithms
for volumetric models of the subvalvular apparatus, in
particular the aortic and
mitral valve. Imaging modalities which offer high spatial
resolution will be
utilized to extract these volumetric models. Furthermore, we
will explore the
value of modalities with high temporal resolution for this
purpose.
| Project manager: Prof. Dr.-Ing. habil. Andreas Maier, Dr. Michael Sühling
Project participants: Dr.-Ing. Dominik Neumann
Keywords: Medical Image Processing;Segmentation;Heart Valve;Cardiovascular Disease;Modeling;Biomechanical Models;Simulation
Duration: 1.1.2013 - 31.12.2015
Sponsored by: Siemens AG, Corporate Technology, Erlangen
Contact: Maier, Andreas Phone +49 9131 85 27883, Fax +49 9131 85 27270, E-Mail: andreas.maier@fau.de
| Publications |
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Neumann, Dominik ; Grbic, Sasa ; Mansi, Tommaso ; Voigt, Ingmar ; Rabbah, Jean-Pierre ; Siefert, Andrew ; Saikrishnan, Neelakantan ; Yoganathan, Ajit ; Yuh, David ; Ionasec, Razvan: Multi-modal Pipeline for Comprehensive Validation of Mitral Valve Geometry and Functional Computational Models. In: Young, Alistair (Ed.) : 4th International Workshop on Statistical Atalses and Computational Models of the Heart (MICCAI STACOM Workshop Nagoya, Japan 26.09.2013). Heidelberg : Springer, 2013, pp n/a. | Neumann, Dominik ; Mansi, Tommaso ; Grbic, Sasa ; Voigt, Ingmar ; Georgescu, Bogdan ; Kayvanpour, Elham ; Amr, Ali ; Sedaghat-Hamedani, Farbod ; Haas, Jan ; Katus, Hugo ; Meder, Benjamin ; Hornegger, Joachim ; Kamen, Ali ; Comaniciu, Dorin: Automatic Image-to-Model Framework for Patient-specific Electromechanical Modeling of the Heart. In: IEEE (Ed.) : 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI) (2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI) Beijing, China 29.04.2014). 2014, pp 935-938. - ISBN 978-1-4673-1961-4 | Zettinig, Oliver ; Mansi, Tommaso ; Neumann, Dominik ; Georgescu, Bogdan ; Rapaka, Saikiran ; Seegerer, Philipp ; Kayvanpour, Elham ; Sedaghat-Hamedani, Farbod ; Amr, Ali ; Haas, Jan ; Steen, Henning ; Katus, Hugo ; Meder, Benjamin ; Navab, Nassir ; Kamen, Ali ; Comaniciu, Dorin: Data-Driven Estimation of Cardiac Electrical Diffusivity from 12-Lead ECG Signals. In: Medical Image Analysis 18 (2014), No. 8, pp 1361-1376 [doi>10.1016/j.media.2014.04.011] | Seegerer, Philipp ; Mansi, Tommaso ; Jolly, Marie-Pierre ; Neumann, Dominik ; Georgescu, Bogdan ; Kamen, Ali ; Kayvanpour, Elham ; Amr, Ali ; Sedaghat-Hamedani, Farbod ; Haas, Jan ; Katus, Hugo ; Meder, Benjamin ; Comaniciu, Dorin: Estimation of Regional Electrical Properties of the Heart from 12-Lead ECG and Images. In: Camara, Oscar ; Mansi, Tommaso ; Pop, Mihaela ; Rhode, Kawal ; Sermesant, Maxime ; Young, Alistair (Ed.) : Proceedings of the 5th International STACOM Workshop (Statistical Atlases and Computational Modeling of the Heart (in conjunction with MICCAI) Cambridge, MA 18.09.2014). Berlin Heidelberg : Springer, 2014, pp 1-9. (LNCS Vol. 8896) | Grbic, Sasa ; Easley, Thomas F ; Mansi, Tommaso ; Bloodworth, Charles H ; Pierce, Eric L ; Voigt, Ingmar ; Neumann, Dominik ; Krebs, Julian ; Yuh, David D ; Jensen, Morten O ; Comaniciu, Dorin ; Yoganathan, Ajit P: Multi-modal Validation Framework of Mitral Valve Geometry and Functional Computational Models. In: Camara, Oscar ; Mansi, Tommaso ; Pop, Mihaela ; Rhode, Kawal ; Sermesant, Maxime ; Young, Alistair (Ed.) : Proceedings of the 5th International STACOM Workshop (Statistical Atlases and Computational Modeling of the Heart (in conjunction with MICCAI) Cambridge, MA 18.09.2014). Berlin Heidelberg : Springer, 2014, pp 239-248. (LNCS Vol. 8896) | Neumann, Dominik ; Mansi, Tommaso ; Georgescu, Bogdan ; Kamen, Ali ; Kayvanpour, Elham ; Amr, Ali ; Sedaghat-Hamedani, Farbod ; Haas, Jan ; Katus, Hugo ; Meder, Benjamin ; Hornegger, Joachim ; Comaniciu, Dorin: Robust Image-Based Estimation of Cardiac Tissue Parameters and Their Uncertainty from Noisy Data. In: Golland, Polina ; Hata, Nobuhiko ; Barillot, Christian ; Hornegger, Joachim ; Howe, Robert (Ed.) : Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2014 (International Conference on Medical Image Computing and Computer-Assisted Intervention Cambridge, MA 09.2014). Boston, USA : Springer, 2014, pp 9-16. |
Institution: Chair of Computer Science 5 (Pattern Recognition)
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