Segmentation of Anatomy and Scar from LGE-MRIThe anatomy of the left ventricle (LV) along with a
detection of scar tissue in the myocardial muscle
provides
important information for the treatment of heart failure.
Heart failure often arises from ventricular dyssynchrony,
when left and right ventricles are not contracting at the
same time. This dyssynchrony can be treated with the
implantation of a bi-ventricular pacemaker in cardiac
resynchronization therapy (CRT). However, the presence of
scar tissue hinders the electrical signal coming from the
CRT device, which negatively affects the success of the
treatment. Integrating the knowledge of the location of
scar
tissue to treatment planning could improve the efficacy
of
CRT.Commonly, Late-Gadolinium-Enhanced (LGE) MR imaging is
performed to visualize both scar tissue and the anatomy
of
the heart. The use of such images for therapeutic
procedures
currently lacks automatic segmentation approaches. Manual
segmentation methods are available, but their use is time
consuming and tedious. Therefore, it would be desirable
if
the segmentation of the myocardium and the scar
classification were completely automatic and independent
of
any manual interaction.
The current research focus is on fully automatic LV
anatomy
and scar segmentation from LGE-MRI. | Project manager:
Prof. Dr.-Ing. habil. Andreas Maier, PD Dr.-Ing. habil. Stefan Steidl, Dr.-Ing. Alexander Brost, Dr.-Ing. Christoph Forman
Project participants:
Dr.-Ing. Tanja Kurzendorfer
Keywords:
Segmentation; Left Ventricle; Late-Gadolinium-Enhanced MRI; Scar Quantification
Duration: 1.10.2015 - 30.9.2018
Contact:
Kurzendorfer, Tanja
Phone +49 9131 85 27874, Fax +49 9131 85 27270, E-Mail: tanja.kurzendorfer@fau.de
| | Publications |
|---|
Kurzendorfer, Tanja ; Brost, Alexander ; Forman, Christoph ; Schmidt, Michaela ; Tillmanns, Christoph ; Hornegger, Joachim: Semi-Automatic Segmentation and Scar Quantification of the Left Ventricle in 3-D Late Gadolinium Enhanced MRI. In: ESMRMB (Ed.) : 32nd Annual Scientific Meeting of the ESMRMB (ESMRMB 2015 Edinburgh 1-3.10). 2015, pp 318-319.
[doi>10.1007/s10334-015-0489-0] | | Kurzendorfer, Tanja ; Forman, Christoph ; Schmidt, Michaela ; Tillmanns, Christoph ; Maier, Andreas ; Brost, Alexander: Fully Automatic Segmentation and Scar Quantification of the Left Ventricle in 3-D Late Gadolinium Enhanced MRI. In: Clifford Weiss, MD, FSIR (Ed.) : Book of Abstracts (11th Interventional MRI Symposium Baltimore 7-8.10). 2016, pp P-03. |
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