Medicinal chemistry A (Pharmaceutical chemistry) (MSM-ME5A)15 ECTS
(englische Bezeichnung: Medicinal chemistry A (Pharmaceutical chemistry))

Lehrveranstaltungen:

• A1: Pharmacopoeia-based analysis of bioactive compounds (1L + 1L)
  • Pharmazeutisch-medizinische Analytik II/Pharmacopeia based analysis (WS 2015/2016)
    (Vorlesung, 1 SWS, Jutta Eichler, Mo, Fr, 9:00 - 10:00, H Inst. Pharm. u. LmCh; Di, 12:00 - 14:00, H Inst. Pharm. u. LmCh; Beginn: 16.10.15; Termine: Mo + Fr vom 16.10.- 6.11.2015, Di vom 10.11.-1.12.2015)
• A2: Pharmaceutical/Medicinal Chemistry (3 L + 3L)
  • Medizinische Chemie A1 (5.+7. Semester) / Medical Chemistry (WS 2015/2016)
    (Vorlesung, 3 SWS, Peter Gmeiner, Di-Do, 9:00 - 10:00, H Biochemie, Fahrstr. 17; Einführungsveranstaltung für Studierende Molecular Science: Do 15.10.2015; 9.15 Uhr; Start der Vorlesung: Di, 20.10.2015)
  • Medizinische Chemie A2 (6.+8. Semester) (SS 2016)
    (Vorlesung, 3 SWS, Peter Gmeiner, Di-Do, 9:00 - 10:00, H Biochemie, Fahrstr. 17; Beginn: 19.4.2016)
• A3: Pharmacopoeia-based analysis of bioactive compounds (7 Lab)
  • Praktikum Arzneibuchanalytik / Practical Pharmacopeia based Analysis (WS 2015/2016)
    (Praktikum, 7 SWS, Jutta Eichler et al., jede Woche Mo-Do, 12:00 - 18:00, Inst. Pharm. u. LmCh; Fr, 12:00 - 15:00, Inst. Pharm. u. LmCh; Beginn/Start:13.10.2015, Vorbesprechung/Introduction: Di, 13.10.2015, 14:00 s.t. in der Alten Bibliothek, Schuhstr. 19, 3 .Stock, Raumnr. 3.003)

Empfohlene Voraussetzungen:

Admission to the M. Sc. programm Molecular Science or Chemistry

Inhalt:

A1: General, as well as substance-specific methods for the qualitative and quantitative analysis (identity, purity, concentration) of drug substances according to the European Pharmacopeia; assessment of physico-chemical properties and reactivities of drug substances, based on their structures; evaluation of the informational value (selectivity, specificity) of individual analysis methods/reactions; special focus: color reactions.
A2: Theoretical knowledge and understanding for the mechanism of action, chemical synthesis, biotransformation, physikochemical properties and SAR studies of the most important drugs and bioactive compound families including: Agents affecting the nervous system, agents with cardiovascular effects, antiallergics, analgesics, antidiabetics, antibiotics, chemotherapeutics and vitamins.
A3: lab course on the pharmaceutical analysis of drugs; determination of identity, purity and quantification

Lernziele und Kompetenzen:

The students

• gain insight into the design, synthesis & development of new drug products in the medicinal/pharmaceutical area

• acquire expertise for the theoretical evaluation and practical application of the most important techniques for the instrumental and bioanalysis of drugs

• are able to reflect crucial theories of the specialty in order to challenge problems in analytical practice.

Literatur:

Online scripts available

Bemerkung:

Intended stage in the degree course: Mandatory elective module (Wahlpflichtmodul) or Elective module (Wahlmodul)
Courses of study for which the module is acceptable: M.Sc. Molecular Life Science

Organisatorisches:

Frequency of offer:
A3: winter term, A1/A2: winter & summer term,

Verwendbarkeit des Moduls / Einpassung in den Musterstudienplan:
Das Modul ist im Kontext der folgenden Studienfächer/Vertiefungsrichtungen verwendbar:

1. Molecular Science (Master of Science)
   (Po-Vers. 2013 | Wahlpflichtmodul Molecular Science)

Studien-/Prüfungsleistungen:

Medizinische Chemie - Ausrichtung Pharmazeutische Chemie (Prüfungsnummer: 30808)

(englischer Titel: Medicinal Chemistry – Focus: Pharmaceutical Chemistry)

Prüfungsleistung, mündliche Prüfung, Dauer (in Minuten): 45, benotet

Anteil an der Berechnung der Modulnote: 100.0 %

weitere Erläuterungen:
Assessment and examinations: Portfolio: LAB (SL, AP), Lab course protocol(s) without marks, presentation, oral examination (45 min, 2 examiners)
Calculation of the grade for the module: 100% from oral examination

Prüfungssprache: Deutsch und Englisch

Erstablegung: SS 2016, 1. Wdh.: WS 2016/2017

1. Prüfer:

Monika Pischetsrieder